Research
1965
1001-5000 Employees
Helmholtz-Zentrum für Infektionsforschung (HZI)ENDURIVAC is bringing together two technologies to develop next generation vaccines.
The main challenge we are working on is waning immunity. Most vaccines require multiple boosters for immunity upkeep and only provide temporary protection. We develop a novel vector platform to provide durable single-shot protection. This vector is based on the murine cytomegalovirus, a murine herpesvirus, which is safe in humans, establishes an antigen depot that continuously trains the immune system and has a huge potential for multivalent vaccines.
We do not only develop the carrier platform, we also engineer antigens to be safer and more effective. Antigens can interact with host factors, such as receptors, which can mask the antigen or lead to undesired side-effects. We have developed a technology that systematically removes undesired binding to receptors while keeping epitopes for potent neutralizing antibodies intact.
These technologies can be combined or produce standalone assets. In our strategic lead programme we develop a vaccine against RSV that is superior to the currently licensed vaccines.
The main challenge we are working on is waning immunity. Most vaccines require multiple boosters for immunity upkeep and only provide temporary protection. We develop a novel vector platform to provide durable single-shot protection. This vector is based on the murine cytomegalovirus, a murine herpesvirus, which is safe in humans, establishes an antigen depot that continuously trains the immune system and has a huge potential for multivalent vaccines.
We do not only develop the carrier platform, we also engineer antigens to be safer and more effective. Antigens can interact with host factors, such as receptors, which can mask the antigen or lead to undesired side-effects. We have developed a technology that systematically removes undesired binding to receptors while keeping epitopes for potent neutralizing antibodies intact.
These technologies can be combined or produce standalone assets. In our strategic lead programme we develop a vaccine against RSV that is superior to the currently licensed vaccines.
Address
Inhoffenstraße 7, 38124 Braunschweig, Germany
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Part of the Lower Saxony Innovation NetworkInnovation promotion and technology transfer - these topics are of particular importance to the state of Lower Saxony. For more than 20 years, Lower Saxony has successfully pursued a strategy of transferring scientific knowledge to the regional economy. Lower Saxony has a comprehensive structure for promoting innovation and business. The partners in the Lower Saxony Innovation Network support companies in particular in realizing innovations, cooperating with research institutions and transforming innovative business ideas into economic success. Universities, technology centers, business development agencies and research institutions are the right partners for all companies that want to increase their innovative capacity. In all regions, the most important sectors and key technologies, Lower Saxony's partners offer companies expert advice and support for their innovation projects.Learn more
Events
In this section you can see events in which the organization participates.
03.11.2026, 16:45 (GMT+01:00)
Innovationspreis NiedersachsenFor the 10th time this year, the Innovationspreis Niedersachsen will be awarded.The Niedersachsen.next Innovationsnetzwerk, together with the Lower Saxony Ministry of Economic Affairs, Transport and Construction and the Lower Saxony Ministry of Science and Culture, honors outstanding ideas, innovative developments, and special collaborations.Be there on November 3rd when this year's award winners are honored and we celebrate the innovative strength of Lower Saxony together.The award ceremony will take place on 3.11. from 5 p.m. in Hanover. More information will follow.
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12.11.2026, 13:00 (GMT+01:00)
Innovationsnetzwerk | Impuls: Startup-Förderung in Niedersachsen auf einen BlickA nationwide network for founders*Ideas arise all over the country – but where exactly can you find the right support to turn an idea into a startup?We at the Innovation Network, together with Niedersachsen.next Startup, would like to give you an overview of the Lower Saxony startup centers and high-tech incubators so that you know which points of contact exist in Lower Saxony.Because Lower Saxony supports startup founders with a dense, nationwide network offering a variety of topics. From artificial intelligence (AI) to GreenTech to Life Science – the innovations of tomorrow are emerging here.We look forward to your participation!
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